This animation shows how a large brain tumor near the pituitary gland can be removed through pioneering endoscopic endonasal (through the nose) surgery at UPMC. This minimally invasive technique allows surgeons to remove skull base tumors as large as softballs through the nose, with less trauma to the brain and critical nerves than with a traditional craniotomy. Learn more: http://brainsurgery.upmc.com
This animation illustrates the removal of a large tumor deep in the brain using the pioneering Neuroendoport(SM) technique at UPMC. The Neuroendoport is a tube the circumference of a dime that creates a pathway for the endoscopic procedure. This minimally invasive technique may be appropriate for tumors in the ventricles as well as the substance of the brain. Learn more: http://brainsurgery.upmc.com
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In a creative stroke inspired by Hollywood wizardry, scientists from the Kishony Lab at HMS and Technion (www.technion.ac.il/en/) have designed a simple way to observe how bacteria move as they become impervious to drugs. The experiments are thought to provide the first large-scale glimpse of the maneuvers of bacteria as they encounter increasingly higher doses of antibiotics and adapt to survive—and thrive—in them. Read the full story at hms.harvard.edu/news/bugs-film Like Harvard Medical School on Facebook: https://goo.gl/4dwXyZ Follow on Twitter: https://goo.gl/GbrmQM Follow on Instagram: https://goo.gl/s1w4up Follow on LinkedIn: https://goo.gl/04vRgY Website: https://hms.harvard.edu
About once a year, on the Oosterscheldekering barrier in the south of the Netherlands, there is NK Tegenwindfietsen: a bicycle race cycling into a headwind. This year it was 120km/h: this is why it's so difficult, and also why it's so brilliant. I'm at https://tomscott.com on Twitter at https://twitter.com/tomscott on Facebook at https://facebook.com/tomscott and on Instagram as tomscottgo
Here's how the surfboard changed our relationship to water, according to fuseproject founder Yves Béhar. Small Thing Big Idea, a TED original series, celebrates the lasting genius of everyday objects so perfectly designed that they changed the world around them. (Made possible with the support of The North Face) Check out more here: https://go.ted.com/STBI and subscribe to our channel here: https://www.youtube.com/TED
Author A.J. Jacobs shows how the coffee cup lid was perfectly designed to give you a full sensory experience while drinking. Small Thing Big Idea, a TED original series, celebrates the lasting genius of everyday objects so perfectly designed that they changed the world around them. (Made possible with the support of The North Face) Check out more here: https://go.ted.com/STBI and subscribe to our channel here: https://www.youtube.com/TED
It’s easy to look at a sleeping dog’s leg twitching and imagine that it’s having a wonderful rabbit-chasing dream. But can animals with brains that are very different from ours have dreams? Hosted by: Stefan Chin SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at http://www.scishowtangents.org ---------- Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Kevin Bealer, KatieMarie Magnone, D.A. Noe, Charles Southerland, Eric Jensen, Christopher R Boucher, Alex Hackman, Matt Curls, Adam Brainard, Scott Satovsky Jr, Sam Buck, Avi Yashchin, Ron Kakar, Chris Peters, Kevin Carpentier, Patrick D. Ashmore, Piya Shedden, Sam Lutfi, charles george, Greg ---------- Looking for SciShow elsewhere on the internet? Facebook: http://www.facebook.com/scishow Twitter: http://www.twitter.com/scishow Tumblr: http://scishow.tumblr.com Instagram: http://instagram.com/thescishow ---------- Sources: Main paper: https://www.nature.com/articles/s41586-019-1336-7.epdf?referrer_access_token=TxDrtALPDcNJn5nA569bc9RgN0jAjWel9jnR3ZoTv0P5iadBs1s4YB5Nx_QJfuD9j6sNPali1XfkDIkaOdEnhD4WmL7_L9EK3Xl8n-KA0SlK9YDW6Fu7_f1LsH_MUKQhgaeFhB1QWX8bJqDJ0meMGs2EXlbwPcUoamBI5RmfGHxAEKeLud-x_Tys2xAN1hUcjzPqf9jBVD_lj5MLtBMRzTnyoy2SXrmmHDZ6h_SGgPE%3D&tracking_referrer=www.pbs.org Other sources: https://www.ncbi.nlm.nih.gov/pubmed/203958 https://www.livescience.com/53743-dog-dreams.html https://www.theatlantic.com/magazine/archive/2019/04/dreams-what-do-they-mean/583216/ https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Understanding-Sleep http://healthysleep.med.harvard.edu/healthy/science/what/sleep-patterns-rem-nrem https://www.nature.com/articles/ncomms8884?con=&dom=pscau&src=syndication Pieron, H. Le Probleme Physiologique su Sommeil (Masson, 1913). https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0050277#s3 http://proberlab.caltech.edu/documents/4-campbell-tobler-1984-1.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777791/ https://www.pbs.org/wgbh/nova/article/zebrafish-sleep/ Images: https://commons.wikimedia.org/wiki/File:Hypro_zyklus_1_en_103.svg https://commons.wikimedia.org/wiki/File:Zebrafish95-300.jpg https://www.istockphoto.com/photo/dog-on-the-bed-gm497385652-79083939 https://www.istockphoto.com/photo/woman-and-fish-gm117150008-15448790 https://www.istockphoto.com/photo/african-american-woman-sleeping-in-bed-gm485559412-72508603 https://www.istockphoto.com/vector/half-moon-stars-and-clouds-on-the-dark-night-sky-background-paper-art-vector-gm928823918-254736959 https://www.istockphoto.com/photo/zebrafish-aquarium-fish-gm505253725-44563946 https://www.istockphoto.com/photo/girl-connected-with-cables-for-eeg-in-front-of-screen-gm94999406-4862934 https://www.istockphoto.com/vector/cute-halloween-ghost-and-black-cat-gm856382208-141182667 https://www.istockphoto.com/vector/home-pet-vector-set-gm1169710289-323457291 https://www.istockphoto.com/vector/moon-and-stars-night-background-banner-gm1083776814-290757864
Help us Improve our content Support us on Patreon : https://www.patreon.com/medsimplfied Urea Cycle Made Simple - Biochemistry Video LIKE US ON FACEBOOK : fb.me/Medsimplified The Urea cycle is a biochemical pathway in which the free ammonia is converted into urea so that it can be easily excreted. Urea is the major end product of nitrogen metabolism in humans. Deficiencies of the various enzymes and transporters involved in the urea cycle can cause urea cycle disorders: N-Acetylglutamate synthase deficiency Carbamoyl phosphate synthetase deficiency Ornithine transcarbamoylase deficiency Citrullinemia (Deficiency of argininosuccinic acid synthase) Argininosuccinic aciduria (Deficiency of argininosuccinic acid lyase) Argininemia (Deficiency of arginase) Hyperornithinemia, hyperammonemia, homocitrullinuria syndrome (Deficiency of the mitochondrial ornithine transporter) Most urea cycle disorders are associated with hyperammonemia, however argininemia and some forms of argininosuccinic aciduria do not present with elevated ammonia. Organisms that cannot easily and quickly remove ammonia usually have to convert it to some other substance, like urea or uric acid, which are much less toxic. Insufficiency of the urea cycle occurs in some genetic disorders (inborn errors of metabolism), and in liver failure. The result of liver failure is accumulation of nitrogenous waste, mainly ammonia, which leads to hepatic encephalopathy. Subscribe : https://www.youtube.com/channel/UCOmrniWfKi-uCD6Oh6fqhgw Watch Again : https://youtu.be/K3rVr_SfXo8 -~-~~-~~~-~~-~- CHECK OUT NEWEST VIDEO: "Nucleic acids - DNA and RNA structure " https://www.youtube.com/watch?v=0lZRAShqft0 -~-~~-~~~-~~-~-
Created by Bianca Yoo. Watch the next lesson: https://www.khanacademy.org/test-prep/nclex-rn/rn-cardiovascular-diseases/rn-dysrhythmia-and-tachycardia/v/atrial-flutter?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn Missed the previous lesson? https://www.khanacademy.org/test-prep/nclex-rn/rn-cardiovascular-diseases/rn-dysrhythmia-and-tachycardia/v/supraventricular-tachycardia?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn NCLEX-RN on Khan Academy: A collection of questions from content covered on the NCLEX-RN. These questions are available under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 United States License (available at http://creativecommons.org/licenses/by-nc-sa/3.0/us/). About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to Khan Academy’s NCLEX-RN channel: https://www.youtube.com/channel/UCDx5cTeADCvKWgF9x_Qjz3g?sub_confirmation=1 Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
What is biliary atresia? Biliary atresia is a condition that affects newborns where the bile ducts become obstructed in some way, potentially from a congenital defect but also by inflammation. Find more videos at http://osms.it/more. Hundreds of thousands of current & future clinicians learn by Osmosis. We have unparalleled tools and materials to prepare you to succeed in school, on board exams, and as a future clinician. Sign up for a free trial at http://osms.it/more. Subscribe to our Youtube channel at http://osms.it/subscribe. Get early access to our upcoming video releases, practice questions, giveaways, and more when you follow us on social media: Facebook: http://osms.it/facebook Twitter: http://osms.it/twitter Instagram: http://osms.it/instagram Our Vision: Everyone who cares for someone will learn by Osmosis. Our Mission: To empower the world’s clinicians and caregivers with the best learning experience possible. Learn more here: http://osms.it/mission Medical disclaimer: Knowledge Diffusion Inc (DBA Osmosis) does not provide medical advice. Osmosis and the content available on Osmosis's properties (Osmosis.org, YouTube, and other channels) do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed health care provider. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition.
Help us Improve our content Support us on Patreon : https://www.patreon.com/medsimplfied Bilirubin Metabolism Simplified LIKE US ON FACEBOOK : fb.me/Medsimplified Please SUPPORT MEDSIMPLIFEID BY BUYING ANYTHINGFROM AMAZON OR FLIPKART USING OUR AFFILIATE LINKS : AMAZON US--- https://goo.gl/XSJtTx AMAZON India http://goo.gl/QsUhku FLIPKART http://fkrt.it/Wiv8RNNNNN FLIPKART MOBILE APP http://fkrt.it/Wiv8RNNNNN Bilirubin (formerly referred to as haematoidin) is a yellow compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates. This catabolism is a necessary process in the body's clearance of waste products that arise from the destruction of aged red blood cells. First the hemoglobin gets stripped of the heme molecule which thereafter passes through various processes of porphyrin catabolism, depending on the part of the body in which the breakdown occurs. For example, the molecules excreted in the urine differ from those in the feces. The production of biliverdin from heme is the first major step in the catabolic pathway, after which the enzyme biliverdin reductase performs the second step, producing bilirubin from biliverdin. Bilirubin is excreted in bile and urine, and elevated levels may indicate certain diseases. It is responsible for the yellow color of bruises and the yellow discoloration in jaundice. Its subsequent breakdown products, such as stercobilin, cause the brown color of feces. A different breakdown product, urobilin, is the main component of the straw-yellow color in urine. Bilirubin is degraded by light. Blood collection tubes containing blood or (especially) serum to be used in bilirubin assays should be protected from illumination. For adults, blood is typically collected by needle from a vein in the arm. In newborns, blood is often collected from a heel stick, a technique that uses a small, sharp blade to cut the skin on the infant's heel and collect a few drops of blood into a small tube. Non-invasive technology is available in some health care facilities that will measure bilirubin by using an instrument placed on the skin (transcutaneous bilirubin meter) Watch Again : https://youtu.be/RwvbO-40xvw Subscribe : https://www.youtube.com/channel/UCOmrniWfKi-uCD6Oh6fqhgw -~-~~-~~~-~~-~- CHECK OUT NEWEST VIDEO: "Nucleic acids - DNA and RNA structure " https://www.youtube.com/watch?v=0lZRAShqft0 -~-~~-~~~-~~-~-
Learn more at http://www.lifetechnologies.com/transfection Optimized protocol for Lipofectamine LTX & Plus reagent: http://tools.invitrogen.com/content/sfs/manuals/LipofectamineLTX_PLUS_Reag_protocol.pdf For technical questions, please reach out to Technical Support at: '[email protected]' or check http://www.invitrogen.com/site/us/en/home/support/Contact-Us.html for contact details. ---------- Audio transcript: How to perform Plasmid DNA transfection with Lipofectamine® LTX and Plus™ Reagent protocol. Superior plasmid delivery and protein expression. In this video, we will perform a plasmid DNA transfection experiment using Lipofectamine® LTX & Plus™ reagent. As always, use good cell culture practices and wear your personal protective equipment. Be sure to clean your cell culture hood and work surface by spraying and wiping them down with 70% ethanol. The day prior to your transfection, seed your cells so that they will be 70% to 90% confluent at the time of your experiment. For this transfection experiment you will need: - Lipofectamine® LTX and Plus™ Reagent - Opti-MEM® Reduced-Serum Medium - Plasmid DNA at 1 microgram per microliter. We will be using a Green Fluorescent Protein plasmid to serve as a positive control for transfection. - Five, 1.5 mL microcentrifuge tubes in a rack - A P200 and P10 pipette and appropriate tips - A marker and a timer - And a 24-well plate with 70% to 90% confluent cells. We will be following the 24-well plate format of the Lipofectamine® LTX & Plus™ Reagent protocol. Prepare 4 tubes each with 50 microliter of Opti-MEM® Medium, and label them 1 to 4. Add 2 microliters of Lipofectamine® LTX Reagent to tube 1, 3 microliters to tube 2, 4 microliters to tube 3 and 5 microliters to tube 4. Mix each tube well by vortexing or flicking the tube. Prepare a tube with 250 microliters of Opti-MEM® medium and add 5 micrograms of plasmid DNA. Since, our DNA concentration is at 1 microgram per mircoliter we are adding 5 microliters. Next add 5 microliters of Plus™ Reagent and mix well. Add 50 microliters of the diluted DNA to each of the Lipofectamine® LTX dilutions in tubes 1 to 4. Incubate the complex for 5 minutes at room temperature. After the 5-minute incubation, remove your 24-well plate containing your cells from the incubator and bring it to the workspace in the hood. Add 50 microliters of the DNA-reagent complex from tubes 1 to 4 to wells 1 to 4 of the 24-well plate, respectively. You should have enough volume to run duplicates on the same plate if desired. Place your 24-well plate back into the incubator and grow cells for 1 to 3 days at 37 Celsius. After incubating your cells, assess the transfection efficiency in each well by viewing GFP fluorescence. Examine each well using a FLoid cell imaging station or microscope to determine which concentration of reagent provided the highest transfection efficiency. In this experiment dilution 3 provided the highest transfection efficiency. For transfection protocols, FAQ's, troubleshooting and tips & tricks visit http://www.lifetechnologies.com/transfection
Created by Jeff Otjen. Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/behavior/human-development/v/gestation?utm_source=YT&utm_medium=Desc&utm_campaign=mcat Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/behavior/human-development/v/implantation?utm_source=YT&utm_medium=Desc&utm_campaign=mcat MCAT on Khan Academy: Go ahead and practice some passage-based questions! About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to Khan Academy’s MCAT channel: https://www.youtube.com/channel/UCDkK5wqSuwDlJ3_nl3rgdiQ?sub_confirmation=1 Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
Eachclip is one of the most popular video-sharing platforms in the United States. Billions of videos have been uploaded and shared on the platform since it was founded in 2013, ranging from Hollywood movie trailers and music videos to amateur vlogs (video blogs) and videos of cats.
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