Ion Torrent™ next-gen sequencing technology

Thermo Fisher Scientific
Subscribers 50,200

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Published on May 20, 2014 at 01:05 am

See how this groundbreaking technology works.

Leveraging consumer technology for scientific breakthroughs

Ion Torrent™ technology takes an entirely new approach to sequencing, making it faster, simpler, and more affordable than ever before.
Unlike other sequencing technologies, Ion Torrent™ systems sequence DNA using a semiconductor chip, similar to the chip found in your digital camera. While the chip in your camera has a sensing layer covered with millions of pixels that translate light into digital information, an Ion chip has millions of wells covering those pixels.
Whenever a nucleotide is incorporated into a single strand of DNA, a hydrogen ion is released. This is how the Ion Torrent system sequences DNA, by reading this chemical change directly in the well on the chip. In essence, each well works as the world's smallest pH meter.